Do I have to clean the entire house?
No. Head lice that fall off a person quickly starve and usually die within 15 hours (and most become incapable of feeding between 3-18 hours off a host). So lice that fall on a desk, floor or coat at school will not be alive the next day. And eggs that may come off a head will not survive. Clothing, stuffed animals, theater seats and other items are not threats to spreading head lice. Bathing every day will not prevent or wash away head lice. Cleaning the home or bagging toys and clothing won’t help you prevent or get rid of head lice.
Washing clothes or bedding of infested individuals is not a bad idea. When doing so, make sure to wash them in hot water (130° F [54.4° C]), then put them in the hot cycle of the dryer for at least 20 minutes.